Sympathetic overactivity in renal disease: a window to understand progression and cardiovascular complications of uraemia?
نویسندگان
چکیده
Keywords: chronic renal failure, sympathetic nervous It is therefore surprising that so far nephrologists have neglected the therapeutic potential of modulating system, hypertension sympathetic nervous activity in chronic renal failure. This is even more strange, since there is convincing evidence to show that in chronic renal failure sympath
منابع مشابه
Sympathetic Overactivity in Chronic Kidney Disease: Consequences and Mechanisms
The incidence of chronic kidney disease (CKD) is increasing worldwide, with more than 26 million people suffering from CKD in the United States alone. More patients with CKD die of cardiovascular complications than progress to dialysis. Over 80% of CKD patients have hypertension, which is associated with increased risk of cardiovascular morbidity and mortality. Another common, perhaps underappr...
متن کاملCardiovascular Risk in Chronic Kidney Disease: Role of the Sympathetic Nervous System
Patients with chronic kidney disease are at significantly increased risk for cardiovascular disease and sudden cardiac death. One mechanism underlying increased cardiovascular risk in patients with renal failure includes overactivation of the sympathetic nervous system (SNS). Multiple human and animal studies have shown that central sympathetic outflow is chronically elevated in patients with b...
متن کاملSoluble Adiponectin is a New Predictor for Cardiovascular Complications in Patients with End Stage Renal Disease
Mortality due to cardiovascular complications (CVC) in patients with end stage renal disease (ESRD) is 20 fold higher than in general population. Adiponectin (ADPN) hormone from adipose tissues accumulation in serum is attributed to reduced renal clearance. The aim of this study was to investigate the possible role of ADPN as a predictor of CVC in adult patients with ESRD on hemodialysis (HD), ...
متن کاملمیزان بروز عوارض مزمن دیابت در بیماران مراجعه کننده به درمانگاه‌های وابسته به دانشگاه علوم پزشکی شیراز در یک دوره 12 ساله
Background: Chronic complications of diabetes causes substantial mortality and morbidity. The incidence and rate of progression of these complications depends on ethnic factors. The aim of this study was to investigate the incidence of late complications of diabetes and its relation to blood glucose control in a group of diabetic patients from South of Iran.Methods: In this retrospective study,...
متن کاملSympathetic activation in chronic renal failure.
The potential involvement of sympathetic overactivity has been neglected in this population despite accumulating experimental and clinical evidence suggesting a crucial role of sympathetic activation for both progression of renal failure and the high rate of cardiovascular events in patients with chronic kidney disease. The contribution of sympathetic neural mechanisms to the occurrence of card...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 15 11 شماره
صفحات -
تاریخ انتشار 2000